Document Type

Patent

Patent Number

US Patent 6,988,446

Patent agency

United States Patent and Trademark Office

Publication Date

1-24-2006

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

10/875,661

Date Filed

2004-06-24

Total Pages

39 pages

Abstract

The present invention provides a novel constitutive nitric oxide synthase (NOS) that utilizes both L-arginine and arginine-rich peptides, oligopeptides or proteins, e.g., bradykinin (BK), as substrates in the synthesis of nitric oxide (NO). Also provided are methods of controlling, regulating or modulating NO synthesis in a subject.

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URL

https://ir.uiowa.edu/patents/389