US Patent 7,135,339
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
The present invention provides novel pseudotyped retroviral vectors that can transduce human and other cells. Vectors are provided that are packaged efficiently in packaging cells and cell lines to generate high titer recombinant virus stocks expressing novel envelope glycoproteins. The present invention further relates to compositions for gene therapy.
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McCray, Paul B Jr and Davidson, Beverly L Methods for producing and using in vivo pseudotyped retroviruses using envelope glycoproteins from lymphocytic choriomeningitis virus (LCMV). US Patent 7,135,339 filed November 20, 2003 and issued November 14, 2006. https://ir.uiowa.edu/patents/413