US Patent 7,220,782
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
The present invention discloses materials and methods useful to treat sensitivity of endothelially-compromised vascular smooth muscle. In one embodiment, CLC3 blockers, particularly compounds of the Formula I are used to treat sensitivity.
Lamb, Fred S. Methods to reduce the sensitivity of endothelially-compromised vascular smooth muscle. US Patent 7,220,782 filed February 25, 2000 and issued May 22, 2007. https://ir.uiowa.edu/patents/424