Inventor

Arthur M. Krieg

Document Type

Patent

Patent Number

US Patent 7,223,741

Patent agency

United States Patent and Trademark Office

Publication Date

5-29-2007

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

10/619,279

Date Filed

2003-07-14

Total Pages

77 pages

Abstract

Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful a synthetic adjuvant.

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URL

https://ir.uiowa.edu/patents/425