Document Type

Patent

Patent Number

US Patent 7,226,766

Patent agency

United States Patent and Trademark Office

Publication Date

6-5-2007

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

09/879,710

Date Filed

2001-06-12

Total Pages

10 pages

Abstract

A method of inhibiting the actions of S-nitrosothiols and nitric oxide which often occur in conditions such as septic shock, chronic or acute pain syndromes, uterine hypotonus, or certain gastrointestinal disorders. The method involving inhibiting the cellular binding of S-nitrosothiols to their cellular receptors or the signal transduction that would result. This is accomplished by administering an S-alkylthiol such as S-methyl-L-cysteine or S-ethyl-L-cysteine to a patient as an antagonist of S-nitrosothiol.

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URL

https://ir.uiowa.edu/patents/427