US Patent 7,332,591
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
The present invention relates to the designation of ADP-ribosylation factor-like 6 as the BBS3 gene, that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypertension, mental retardation, renal cancer and other abnormalities, retinopathy and hypogonadism. Methods of use for the gene, for example in diagnosis and therapy of BBS and in drug screening, also are described.
Creative Commons License
This work has been identified with a Creative Commons Public Domain Mark 1.0.
Sheffield, Val C; Stone, Edwin; Casavant, Thomas; Braun, Terry; and Nishimura, Darryl Bardet-Biedl susceptibility gene and uses thereof. US Patent 7,332,591 filed December 21, 2004 and issued February 19, 2008. https://ir.uiowa.edu/patents/447