US Patent 7,470,777
United States Patent and Trademark Office
Iowa State University Research Foundation, Inc. (Ames, IA, US) ; University of Iowa Research Foundation (Iowa City, IA, US)
Embodiments of the invention include compositions comprising and methods utilizing a retroviral integrase complex comprising a recombinant integrase having a domain comprising a non-native protein binding site, and a DNA binding protein comprising a DNA binding domain and a peptide binding domain that binds the non-native protein binding site of the recombinant integrase.
Mccray Jr., Paul B.; Sinn, Patrick L.; Voytas, Daniel F.; and Dai, Junbiao Compositions and methods related to modified retroviral vectors for restricted, site specific integration. US Patent 7,470,777 filed December 22, 2005 and issued December 30, 2008. https://ir.uiowa.edu/patents/468