Document Type

Patent

Patent Number

US Patent 7,488,490

Patent agency

United States Patent and Trademark Office

Publication Date

2-10-2009

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

10/023,909

Date Filed

2001-12-18

Total Pages

58 pages

Abstract

The present invention relates generally to adjuvants, and in particular to methods and products utilizing a synergistic combination of immunostimulatory oligonucleotides having at least one unmethylated CpG dinucleotide (CpG ODN) and a non-nucleic acid adjuvant. Such combinations of adjuvants may be used with an antigen or alone. The present invention also relates to methods and products utilizing immunostimulatory oligonucleotides having at least one unmethylated CpG dinucleotide (CpG ODN) for induction of cellular immunity in infants.

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URL

https://ir.uiowa.edu/patents/471