Document Type

Patent

Patent Number

US Patent 7,649,089

Patent agency

United States Patent and Trademark Office

Publication Date

1-19-2010

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

10/975,248

Date Filed

2004-10-28

Total Pages

22 pages

Abstract

A new cellulose excipient, OCCAE, suitable for use as a binder, filler, and/or disintegrant in the development of solid dosage forms and as a bodying agent or a drug carrier in the preparation of topical formulations is described. The cellulose excipient is formed by reacting an oxidized cellulose ester with an alcohol in the presence of a catalyst. The invention also describes the formation of controlled release microspheres using OCCAE and/or oxidized cellulose esters that may be used to control the release of drug in a patient over a time period of several hours to several days.

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URL

https://ir.uiowa.edu/patents/494