US Patent 7,728,001
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
The invention provides novel compounds of formula I: that are opioid receptor ligands. The invention also provides pharmaceutical compositions comprising such compounds as well as methods for treating diseases associated with opioid receptor function by administering such compounds to a mammal in need of treatment. The invention also provides an improved method for isolating intermediate materials useful for obtaining compounds of formula I.
Prisinzano, Thomas and Rothman, Richard Brian Opioid receptor ligands and methods for their preparation. US Patent 7,728,001 filed September 12, 2005 and issued June 01, 2010. https://ir.uiowa.edu/patents/512