Document Type
Patent
Patent Number
US Patent 7,741,469
Patent agency
United States Patent and Trademark Office
Publication Date
6-22-2010
Assignee
University of Iowa Research Foundation (Iowa City, IA, US)
Application Number
11/732,619
Date Filed
2007-04-04
Total Pages
45 pages
Abstract
This invention also relates to compounds, compositions, and methods useful for modulating the expression and activity of genes encoding proteins involved in deafness caused by dominant negative mechanism of action by RNA interference (RNAi) using small nucleic acid molecules. In particular, the instant invention features small nucleic acid molecules, such as short interfering nucleic acid, short interfering RNA, double-stranded RNA (dsRNA), micro-RNA (mRNA), and short hairpin RNA (shRNA) molecules and methods used to modulate the expression of genes involved in deafness caused by dominant negative mechanism of action.
Creative Commons License
This work has been identified with a Creative Commons Public Domain Mark 1.0.
Recommended Citation
Smith, Richard J Compositions for treating hearing loss and methods of use thereof. US Patent 7,741,469 filed April 04, 2007 and issued June 22, 2010. https://ir.uiowa.edu/patents/513
URL
https://ir.uiowa.edu/patents/513