US Patent 8,012,683
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US) ; The Trustees of Columbia University in the City of New York (New York, NY, US) ; United States of America, as represented by the Secretary of the Department of Health and Human Services (Washington, DC, US)
Methods for identifying a subject at risk for developing AMD are disclosed, as are kits which can be used to practice the methods. The methods include identifying specific protective or risk polymorphisms or genotypes from the subject's genetic material, including polymorphisms in the BF, C2 and/or CFH genes. Microarrays and kits for use in these methods are also provided.
Allikmets, Rando L.; Hageman, Gregory S.; Dean, Michael C.; and Gold, Albert M. Variants in complement regulatory genes predict age-related macular degeneration. US Patent 8,012,683 filed February 13, 2007 and issued September 06, 2011. https://ir.uiowa.edu/patents/550