Document Type
Patent
Patent Number
US Patent 8,202,688
Patent agency
United States Patent and Trademark Office
Publication Date
6-19-2012
Assignee
University of Iowa Research Foundation (Iowa City, IA, US) ; Coley Pharmaceutical GmbH (Düsseldorf, DE) ; Ottawa Health Research Institute (Ottawa, CA)
Application Number
10/300,247
Date Filed
2002-11-20
Total Pages
56 pages
Abstract
The present invention relates generally to adjuvants, and in particular to methods and products utilizing a synergistic combination of immunostimulatory oligonucleotides having at least one unmethylated CpG dinucleotide (CpG ODN) and a non-nucleic acid adjuvant. Such combinations of adjuvants may be used with an antigen or alone. The present invention also relates to methods and products utilizing immunostimulatory oligonucleotides having at least one unmethylated CpG dinucleotide (CpG ODN) for induction of cellular immunity in infants.
Creative Commons License
This work has been identified with a Creative Commons Public Domain Mark 1.0.
Recommended Citation
Davis, Heather L; Schorr, Joachim; and Krieg, Arthur M Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant. US Patent 8,202,688 filed November 20, 2002 and issued June 19, 2012. https://ir.uiowa.edu/patents/571
URL
https://ir.uiowa.edu/patents/571