Document Type

Patent

Patent Number

US Patent 8,282,918

Patent agency

United States Patent and Trademark Office

Publication Date

10-9-2012

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

12/671,356

Date Filed

2008-07-29

Total Pages

48 pages

Abstract

Disclosed are polynucleotides and polypeptides that are useful for assessing and modulating cell proliferation. The polynucleotides may comprise coding regions for RPA4 and RPA4/RPA32 hybrid polypeptides. The polynucleotides may be used in gene vectors for modulating cell proliferation in a patient in need thereof. Diagnostic methods related to assaying RPA4 expression in test samples in order to detect proliferating or cancerous cells also are disclosed.

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URL

https://ir.uiowa.edu/patents/584