US Patent 8,343,911
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
The invention presented herein provides methods and compositions for the prevention and treatment of bacterial infections. The methods are based on the discovery that depletion of bioavailable iron stimulates surface motility in bacteria thus inhibiting the ability of a bacterial population to develop into a biofilm.
Singh, Pradeep K.; Welsh, Michael J.; and Greenberg, Peter E. Methods of inhibiting and treating bacterial biofilms by metal chelators. US Patent 8,343,911 filed October 20, 2008 and issued January 01, 2013. https://ir.uiowa.edu/patents/591