US Patent 9,422,248
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
A substituted phenol compound represented by Formula I: or a pharmaceutically acceptable salt or prodrug thereof. At least one of X and Y is CH, and the other one of X and Y is N or CH. R1 is C1-C4 alkyl or C1-C4 haloalkyl. R2 is C1-C4 alkyl, or halogen. R3 is H, C1-C4 alkyl, aryl, or —(CH2)n-aryl, in which n is 1, 2, or 3. The compound is useful as anticonvulsant.
Baker, Max T. and Mishra, Rajesh K. Phenyl- and pyridinyl-substituted 2,2,2-trifluoroethanols having anticonvulsant properties. US Patent 9,422,248 filed June 13, 2013 and issued August 23, 2016. https://ir.uiowa.edu/patents/669