US Patent 4,847,338
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
There is disclosed a tetrasaccharide, a hexasaccharide, on octasaccharide and a decasaccharide all capable of inhibiting complement activation and having less tha 33% of undigested native heparin's anticoagulation activity.
Linhardt, Robert J.; Merchant, Zohar M.; Weiler, John M.; and Sharath, Murali Low molecular weight heparin fragments as inhibitors of complement activation. US Patent 4,847,338 filed June 17, 1987 and issued July 11, 1989. https://ir.uiowa.edu/patents/67