US Patent 9,572,894
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
The present invention provides three-component compositions comprising microparticles, a tumor antigen, a first immune adjuvant, and a second immune adjuvant. Also provided are chemo-immunotherapeutic compositions comprising microparticles, a chemotherapeutic agent, and an immune adjuvant.
Salem, Aliasger K.; Geary, Sean M.; Weiner, George J.; Lemke, Caitlin; and Krishnamachari, Yogita Biodegradable particulate formulations. US Patent 9,572,894 filed October 18, 2011 and issued February 21, 2017. https://ir.uiowa.edu/patents/681