US Patent 9,650,631
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
The present invention is directed to RNA interference (RNAi) molecules targeted against a nucleic acid sequence, and methods of using these RNAi molecules to reduce off-target toxicity.
Davidson, Beverly L.; Mas Monteys, Alejandro; Mcbride, Jodi L.; and Boudreau, Ryan Reduction of off-target RNA interference toxicity. US Patent 9,650,631 filed August 27, 2013 and issued May 16, 2017. https://ir.uiowa.edu/patents/688