US Patent 9,758,781
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
The present invention provides in certain embodiments a method of treating autosomal dominant non-syndromic hearing loss (ADNSHL) in a patient in need thereof comprising: (a) identifying a mutation in an ADNSHL-causing gene, (b) preparing a ADNSHL therapeutic miRNA, and (c) administering to the patient a pharmaceutical composition comprising the ADNSHL therapeutic miRNA and a pharmaceutically acceptable carrier.
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Smith, Richard J H and Shibata, Seiji Methods to prevent and treat autosomal dominant non-syndromic hearing loss. US Patent 9,758,781 filed September 10, 2015 and issued September 12, 2017. https://ir.uiowa.edu/patents/695