Document Type

Patent

Patent Number

US Patent 4,916,219

Patent agency

United States Patent and Trademark Office

Publication Date

4-10-1990

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

07/227,357

Date Filed

1988-08-02

Total Pages

12 pages

Abstract

There is disclosed oligosaccharide compounds having heparin-like anticomplement activity and reduced anticoagulant activity as compared with heparin on a weight or molar basis. The oligosaccharide compounds have at least 5 and no greater than 25 saccharide units. The oligosaccharides can have an even nuber of saccharide units with a terminus nonreducing sugar, or an odd number of saccharide units without a terminus nonreducing sugar. There is also disclosed anticomplement pharmaceutical compositions with reduced anticoagulant side effect activity and a process for preparing the oligosaccharide compounds.

Share

COinS
 

URL

https://ir.uiowa.edu/patents/74