Document Type

Patent

Patent Number

US Patent 4,975,449

Patent agency

United States Patent and Trademark Office

Publication Date

12-4-1990

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

06/464,063

Date Filed

1983-02-04

Total Pages

8 pages

Abstract

A topical composition for eye treatment of glaucoma, comprising a small but pharmaceutically effective amount of an analog of benzothiazole-2-sulfonamide. The most preferred compound is 6-chloro-benzothiazole-2-sulfonamide. The invention also relates to a method of topically treating glaucoma with eye drops to reduce intraocular pressure. Finally, disclosed is a method of synthesis of the preferred and highly effective benzothiazole-2-sulfonamide analogs, particularly the 6-chloro-benzothiazole-2-sulfonamide compound.

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URL

https://ir.uiowa.edu/patents/81