US Patent 5,147,776
United States Patent and Trademark Office
University of Iowa Research Foundation (Iowa City, IA, US)
2,5-anhydro-D-mannitol is added to blood platelet storage containers at a sufficient level to maintain pH stability of blood platelets within the suitable range (pH 7.2 to 7.4) for use in blood transfusions.
Koerner Jr., Theodore A. W. Use of 2,5-anhydromannitol for control of pH during blood storage. US Patent 5,147,776 filed February 26, 1990 and issued September 15, 1992. https://ir.uiowa.edu/patents/96