Document Type

Patent

Patent Number

US Patent 5,157,044

Patent agency

United States Patent and Trademark Office

Publication Date

10-20-1992

Assignee

University of Iowa Research Foundation (Iowa City, IA, US)

Application Number

07/535,573

Date Filed

1990-06-11

Total Pages

6 pages

Abstract

Analogs are prepared of the carbonic anhydrase inhibitors methazolamide, and dichlorphenamide. The analogs link a cleavable functional group to the pharmacologically active carbonic anhydrase inhibitor resulting in compounds of improved corneal permeability, which are non-irritable to the eye and which are effective topically to inhibit intraocular pressure.

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URL

https://ir.uiowa.edu/patents/97