US Patent 5,168,062
United States Patent and Trademark Office
University of Iowa Research Foundation (Oakdale, IA, US)
The cloning of a eucaryotic promoter-regulatory region that functions preferentially in human cells is disclosed. The invention is exemplified by the cloning of a section of the human cytomegalovirus genome comprising a DNA sequence with regulatory and promoter signals and an initiation site for RNA synthesis. The fragment, termed the human cytomegalovirus (HCMV) promoter-regulatory sequence, was obtained from purified HCMV DNA.
Stinski, Mark F. Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence. US Patent 5,168,062 filed September 10, 1990 and issued December 01, 1992. https://ir.uiowa.edu/patents/99