Zmiz1 staining is elevated in patients with epithelial ovarian cancer. Tumors that are Zmiz1 positive are associated with mutations of the p53 gene. Zmiz1 overexpression may be associated with decreased survival in patients with epithelial ovarian cancer. Additional studies are needed to more clearly determine the role of Zmiz1 in patients with epithelial ovarian cancer.
Zmiz1, ovarian cancer, P53 mutations
Copyright © Niyati J. Nadkarni, Laura M. Rogers, Megan Samuelson, Traci Neff, David J. Bender, Amina Ahmed, Koen De Geest, Anna Button, Adam Dupay, Michael J. Goodheart, 2011.
Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.
Nadkarni NJ, Rogers LM, Samuelson M, Neff T, Bender DP, Ahmed A, De Geest K, Button A, Dupuy A, Goodheart M. Zmiz1 is overexpressed in epithelial ovarian cancer and associated with p53 gene mutations. Proc Obstet Gynecol. 2011 Jul 28;2(1):Article 12 [2 p.]. https://doi.org/10.17077/2154-4751.1108. Free full text article.