Objective: Angiosarcoma is a rare neoplasm typically presenting in the skin and superficial soft tissues, with an equal female-to-male ratio. We present a woman with recurrent vulvar lesions and a history of melanoma found to have angiosarcoma.
Case: A 67-year-old woman presented with a seven month history of recurrent vulvar lesions with symptoms of discomfort and bleeding. The histopathological diagnosis revealed high-grade angiosarcoma. Computed tomographic imaging with contrast and positron emission tomography revealed disseminated disease. She underwent chemotherapy and radiation but died within one year of diagnosis.
Conclusions: The prognosis for patients with angiosarcoma is generally poor, especially with disseminated disease. Early detection remains the key element in maximizing patient outcomes.
Angiosarcoma, vulvar angiosarcoma, sarcoma, melanoma
The authors report no conflict of interest.
Copyright © 2014 Ashley Lafever, Eric M. Tyler, and Colleen K. Stockdale
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Lafever A, Tyler EM, Stockdale CK. Angiosarcoma of the vulva. Proc Obstet Gynecol. 2014 Oct 30;4(2):Article 9 [4 p.]. https://doi.org/10.17077/2154-4751.1254. Free full text article.