Background: In recent years the rate of cesarean section has significantly increased.To determine the efficacy of prophylactic antibiotics in reducing infectious morbidity after cesarean section.
Objectives: In our study, we aimed to evaluate the efficiency of prophylactic antibiotic administration by comparing three groups using single, multiple and no prophylactic antibiotic therapy.
Materials and Methods: Our study is a prospective, randomized controlled study including emergent cases, that developed cesarean indication while in active labor, and elective cesarean cases. A total of 90 patients were included in the study, including 30 patients who underwent cesarean delivery and did not undergo an antibiotic prophylaxis (Group 1), 30 patients who underwent a single dose antibiotic prophylaxis (Group II) and 30 patients who underwent multiple dose antibiotic prophylaxis (Group III).
Results: The incidence of wound infection was significantly higher in cases that were not using antibiotics at postoperative days 3, 5 and 7 compared to the cases using single and multiple antibiotics. There was not a significant difference between groups in terms of endometritis.
Conclusion: Administration of prophylactic antibiotics prevent wound infection but does not prevent development of endometritis.
Antibiotic prophylaxis, infection, cesarean section
The authors report no conflict of interest.
Copyright © 2016 the authors
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Hafızoğlu RK, Kumbasar S, Şık BA, Bozkurt M, Ulaş M, Yumru AE, Dinçgez B, Salman S. Evaluation of the efficiency of antibiotic prophylaxis in cesarean cases. Proc Obstet Gynecol. 2016 Mar 28;6(1):Article 1 [10 p.]. https://doi.org/10.17077/2154-4751.1309. Free full text article.