Uterine rupture is a disastrous obstetric complication, occurring mostly in the second and third trimesters. The risk of uterine rupture markedly increases with previous uterine surgeries. Termination of early pregnancy failure using misoprostol is common. However, its use in women with a scarred uterus is speculative and usually puts the obstetricians in a stressful situation. Here we present a case of rupture of a scarred uterus in the first trimester after sublingual misoprostol. A 35 years old multiparous woman presented with uterine rupture after administration of small doses of sublingual misoprostol for termination of early pregnancy failure. Immediate laparotomy was done and the defect was repaired. Termination of early pregnancy failure, in women with a scarred uterus, using sublingual misoprostol can lead to uterine rupture. Sublingual misoprostol should be used cautiously under close supervision or other routes (vaginal or oral) should be used instead.
Uterine rupture, misoprostol, scarred uterus, maternal morbidity
The authors report no conflict of interest.
Copyright © 2016 the authors
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Abbas AM, Sheha AM, Hussein RS, Talaat E, Ali MN. First-trimester rupture of a scarred uterus after use of sublingual misoprostol: a case report. Proc Obstet Gynecol. 2016 Aug 18;6(2):Article 5 [6 p.]. https://doi.org/10.17077/2154-4751.1317. Free full text article.