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Abstract

Objective: To evaluate complete blood count (CBC) changes that suggest coronavirus disease-2019 (COVID-19) among asymptomatic pregnant women attending routine antenatal care

Methods: A cross-sectional study included 187 healthy pregnant women who were attending the antenatal care clinic of a tertiary University hospital between March and June 2020. After a thorough history and examinations, a venous blood sample was taken from each participant for complete and differential blood counts. Those who showed CBC findings suggestive of COVID-19 were further scheduled for a nasopharyngeal swab for detection of SARS- CoV-2 specific antigens through polymerase chain reaction (PCR).

Results: We found 5.3% (n=10) of the study population showed CBC changes that are suggestive of COVID-19. When they were scheduled for nasopharyngeal swab for a PCR confirmatory test, 30% (n=3) of them were PCR positive (which represented 1.6% of the entire study population). The most frequently encountered COVID-19-suggestive change in peripheral blood leukocyte differential counts was leucopenia (100%), followed by decreased eosinophil count (50%), then neutropenia and lymphocytopenia (30%).

Conclusions: Certain differential leucocyte count changes (leucopenia, neutropenia, lymphocytopenia and decreased eosinophil count) among asymptomatic pregnant women might be related to COVID-19 infection and may indicate a need for further testing.

Keywords

COVID-19, pregnancy, blood count

Total Pages

9

Financial Disclosure

The author reports no conflict of interest.

Submission Type

Article

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.

Publisher

Department of Obstetrics and Gynecology, The University of Iowa Hospitals and Clinics

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URL

https://ir.uiowa.edu/pog_in_press/120