Association between recurrent bacterial vaginosis and Helicobacter pylori infection: a case report

Joshua Bleicher, University of Iowa Carver College of Medicine, Iowa City, Iowa
Colleen K. Stockdale, University of Iowa Hospitals and Clinics, Department of Obstetrics and Gynecology, Iowa City, Iowa


Background: Nearly one in three women in the United States are affected by bacterial vaginosis at some point in their life, with more than fifty percent experiencing recurrent symptoms within 12 months.

Case: A 36 year old G9P2072 with 1 year history of recurrent bacterial vaginosis despite repeated treatments with local and systemic metronidazole, metronidazole suppression, and probiotic therapy had relief of bacterial vaginosis following triple antibiotic therapy for Helicobacter pylori. She remains asymptomatic for both bacterial vaginosis and Helicobacter pylori at 6 month follow up.

Discussion: We present a woman with recurrent bacterial vaginosis who had sudden relief of her symptoms following treatment for Helicobacter pylori. While association should not be construed as causation, similar pathogenesis may warrant investigation of H pylori as a potential cause of the complex change in the vaginal flora leading to bacterial vaginosis.